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GS2: Robert J. Genco Perio Systemic Symposium

November 10, 2023 @ 3:30 pm - 5:30 pm


W. Sue T. Griffin

Alpdogan Kantarci

Aimee Kao

Mark I. Ryder


William V. Giannobile

Course Description

There is mounting evidence regarding the bi-directional link between periodontal disease and Alzheimer’s Disease. Within the Alzheimer’s Disease research field there is a growing consensus for the need to identify upstream causation events prior to the irreversible pathological changes in the brain. Among the putative mediators are the potential role of translocation to the brain of periodontitis-associated pathogens, such as Porphyromonas gingivalis, and their products. The basic clinical criteria for Alzheimer’s Disease as well as other common neurodegenerative disorders will be highlighted in this perio-systemic program. The program presentations will cover the current and future therapeutic landscapes and practical adjustments for periodontists when treating individuals with memory and other cognitive disorders.

Educational Objectives:

• Understand the link between periodontal disease and Alzheimer’s disease.
• Review the cognitive manifestations of Alzheimer’s Disease and other major neurodegenerative diseases such as vascular dementia and Lewy Body Disease.
• Understand the clinical implications of the link between oral and systemic diseases.
• Describe how results from laboratory, preclinical, and human studies on the potential role of P. gingivalis may guide the clinician in developing current and future personalized dental approaches to patients at risk for developing Alzheimer’s disease.


Thank you to Crest + Oral-B for sponsoring this year’s Robert J. Genco Perio Systemic Symposium


November 10, 2023
3:30 pm - 5:30 pm
Program Track:


American Academy of Periodontology